Shiel now offering the oncoFISH Cervical test to assist in the clinical management of LSIL prior to colposcopy.

Shiel now offers offers the oncoFISH cervical test, a laboratory developed test by Ikonisys Labs, which can be used in conjunction with other testing to better manage patients previously diagnosed with an LSIL result. oncoFISH cervical is available exclusively from Ikonisys Clinical Laboratories.

The oncoFISH cervical test is an automated qualitative fluorescence in situ hybridization (FISH) test for determining the acquisition of specific chromosomal aneuploidies within the 3q26 region in cytological specimens revealing LSIL.

oncoFISH cervical provides information to assist the physician in the clinical management of LSIL prior to colposcopy.

Approximately 10% of patients diagnosed with LSIL will progress to HSIL, 60% will regress to normal and 30% will remain LSIL (Nasiell K, et al. 1986, Ostor AG, et al. 1993, Melnikow J, et al. 1998, Holowaty P, et al. 1999, Wright TC, et al. 2007.)

Historically, it has not been possible to identify which patients will progress or not. The oncoFISH cervical test provides a predictive tool to aid the clinician in managing an LSIL diagnosis.

It is recommended that the physician use the oncoFISH cervical test results as part of the patient's overall clinical assessment and in the context of current clinical practice guidelines. oncoFISH cervical is not intended to be used as a stand-alone test.

Shiel Test Ordering Info:

OncoFISH can be ordered as an individual test from either a ThinPrep or SurePath specimen:

Test # 1910 - oncoFSH Cervical.

OncoFISH can be a reflex test from a Surepath plus HPV Hi Risk, or ThinPrep plus HPV Hi Risk

ThinPrep Test #:	78821 - ThinPrep + HPV Hi
Surepath Test#:	88821 - Surepath + HPV Hi

The reflex to oncoFISH will occur:

1. An ASCUS Pap together with a Positive HPV Hi Risk, or

2. Any Pap with an LGSIL diagnosis

For additional info click this link: http://www.ikonisys.com/cervical/Overview_us.html